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Overview

HIVE is an Add-on for the VANTED system. VANTED is a graph editor extended for the visualisation and analysis of biological experimental data in context of pathways/networks. HIVE stands for

Handy Integration and Visualisation of multimodal Experimental Data

and extends the functionality of VANTED by adding the handling of volumes and images, together with a workspace approach, allowing one to integrate data of different biological data domains.

HIVE is written in Java and Java3D and utilize Software Design patterns such as the Model-View-Controller concept. To understand how the application can be used, you may watch a demo video. The main tasks of HIVE are:

• handling of omics data
  • metabolomics
  • proteomicss
  • transcriptomicss
  • genomics
• handling of networks
  • gene regulatory networks
  • biological pathways
  • network maps and diagrams
  • metabolic and biochemical reaction networks
  • signal transduction networks
  • protein interaction networks
• handling of images
  • histological cross-sections
  • in situ hybridization
  • electron microscopy and light microscopic
  • phenotypic photographs
• handling of volumes
  • NMR imaging, CT or MRT/MRI
  • cross-section stacks
  • microscopy stacks
• integration these different data types using a graph-based workspace
• combining biological data in different ways and
• manifold visualisations of combined data

Publications

• Hendrik Rohn, Christian Klukas, Falk Schreiber (2011)
  Creating Views on Integrated Multidomain Data
  Bioinformatics, 27 (13): 1839-1845
• Hendrik Rohn, Christian Klukas, Falk Schreiber (2011)
  Visual Analytics of Multimodal Biological Data
  Proceedings of the International Conference on Information Visualization Theory and Applications, SciTePress: 256-261
• Hendrik Rohn, Christian Klukas, Falk Schreiber (2009)
  Integration and Visualisation of Multimodal Biological Data
  Proceedings of the German Conference on Bioinformatics, LNI 157: 105-115